Rhinorrhea, cough and fatigue in patients taking sitagliptin

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Rhinorrhea, cough and fatigue in patients taking sitagliptin

Sitagliptin is a dipeptidyl peptidase-4 (DPP IV, CD26) inhibitor indicated for treatment of Type II diabetes as a second line therapy after metformin. We report fifteen sitagliptin intolerant patients who developed anterior and posterior rhinorrhea, cough, dyspnea, and fatigue. Symptoms typically developed within 1 to 8 weeks of starting, and resolved within 1 week of stopping the drug. Peak ex...

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Improvement of cancer related fatigue in breast and colorectal cancer patients taking part in mindfulness based stress reduction

Abstract Object: one of the most common and disruptive symptoms experienced by cancer survivors is cancer related fatigue. This symptom can persist many years after cancer diagnosis, leading to reduced performance, quality of life, and significant socioeconomic outcomes. Therefore, the aim of this study is to answer the question of whether mindfulness –based stress reduction on cancer related f...

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Allergy, Asthma & Clinical Immunology

Sitagliptin is a dipeptidyl peptidase-4 (DPP IV, CD26) inhibitor indicated for treatment of Type II diabetes as a second line therapy after metformin. We report fifteen sitagliptin intolerant patients who developed anterior and posterior rhinorrhea, cough, dyspnea, and fatigue. Symptoms typically developed within 1 to 8 weeks of starting, and resolved within 1 week of stopping the drug. Peak ex...

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Cough frequency, cough sensitivity and health status in patients with chronic cough.

BACKGROUND Little is known about the frequency of cough in health and in patients with chronic cough. METHODS We measured cough frequency and its relationship with other markers of cough severity in 20 patients with chronic cough and 9 healthy subjects using the Leicester Cough Monitor (LCM), which is an automated ambulatory digital cough monitor that records sound only. All subjects had a 6-...

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Effects of 6-Month Sitagliptin Treatment on Metabolic Parameters in Diabetic Patients Taking Oral Glucocorticoids: A Retrospective Cohort Study

BACKGROUND There are no guidelines for the treatment of diabetes in patients taking glucocorticoids. We studied to understand the effects of 6-month treatment with sitagliptin on metabolic parameters in diabetic patients taking glucocorticoids. METHODS We retrospectively picked up patients who had been prescribed sitagliptin for 6 months during the continuous prescription of oral glucocortico...

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ژورنال

عنوان ژورنال: Allergy, Asthma & Clinical Immunology

سال: 2010

ISSN: 1710-1492

DOI: 10.1186/1710-1492-6-8